Maker —
No US authorization
Decision—Studies450Trials49
Injectables — 26 products on the FDA record
34 of 136 products · 18 PMA · 7 BLA · 1 NDA · 8 No US authorization
34 products
Maker —
No US authorization
Decision—Studies2,396Trials79
Tiger Aesthetics Medical, LLC
PMA · approvedP020012
Approved2006Studies—Trials—
Merz North America, Inc.
PMA · approvedP090016
Approved2011Studies1,298Trials46
Merz North America, Inc.
PMA · approvedP250016
Approved2026Studies1,298Trials46
Merz North America, Inc.
PMA · approvedP250020
Approved2026Studies1,298Trials46
ALLERGAN
BLA · approvedBLA103000
Approved1991Studies2,201Trials186
Maker —
No US authorization
Decision—Studies158Trials106
REVANCE THERAPEUTICS, INC.
BLA · approvedBLA761127
Approved2022Studies2,201Trials186
IPSEN BIOPHARM LTD
BLA · approvedBLA125274
Approved2009Studies2,201Trials186
Maker —
No US authorization
Decision—Studies—Trials—
Maker —
No US authorization
Decision—Studies158Trials106
HALOZYME THERAP
BLA · approvedBLA021859
Approved2005Studies—Trials—
EVOLUS INC
BLA · approvedBLA761085
Approved2019Studies2,201Trials186
Maker —
No US authorization
Decision—Studies158Trials106
Allergan
PMA · approvedP050047
Approved2010Studies1,298Trials46
Allergan
PMA · approvedP110033
Approved2016Studies1,298Trials46
Allergan
PMA · approvedP110033
Approved2017Studies1,298Trials46
Allergan
PMA · approvedP110033
Approved2013Studies1,298Trials46
Allergan
PMA · approvedP110033
Approved2022Studies1,298Trials46
ABBVIE
NDA · approvedNDA206333
Approved2015Studies—Trials—
HUGEL INC
BLA · approvedBLA761225
Approved2024Studies2,201Trials186
Maker —
No US authorization
Decision—Studies1,298Trials46
Merz North America, Inc.
PMA · approvedP050037
Approved2006Studies582Trials7
Maker —
No US authorization
Decision—Studies155Trials16
Q-Med AB
PMA · approvedP140029EU
Approved2016Studies1,298Trials46
Q-Med AB
PMA · approvedP140029EU
Approved2020Studies1,298Trials46
Q-Med AB
PMA · approvedP040024EU
Approved2015Studies1,298Trials46
Q-Med AB
PMA · approvedP040024
Approved2014Studies1,298Trials46
Prollenium Medical Technologies, Inc.
PMA · approvedP160042
Approved2017Studies1,298Trials46
Teoxane S.A.
PMA · approvedP170002
Approved2017Studies1,298Trials46
Q-Med AB
PMA · approvedP030050EU
Approved2004Studies586Trials17
Allergan
PMA · approvedP110033
Approved2023Studies1,298Trials46
MERZ PHARMS
BLA · approvedBLA125360
Approved2010Studies2,201Trials186
| Product | Manufacturer | Category | Pathway | Class | First decision | Studies | Trials |
|---|---|---|---|---|---|---|---|
| AestheFill | — | Injectables | No US authorization found | — | — | 450 | 49 |
| ASCE+ | — | Injectables | No US authorization found | — | — | 2,396 | 79 |
| Bellafill | Tiger Aesthetics Medical, LLC | Injectables | PMA — approved | — | Oct 27 2006 | — | — |
| Belotero Balance | Merz North America, Inc. | Injectables | PMA — approved | — | Nov 14 2011 | 1,298 | 46 |
| Belotero Intense (+) Lidocaine | Merz North America, Inc. | Injectables | PMA — approved | — | Jul 9 2026 | 1,298 | 46 |
| Belotero Volume (+) Lidocaine | Merz North America, Inc. | Injectables | PMA — approved | — | May 19 2026 | 1,298 | 46 |
| Botox Cosmetic | ALLERGAN | Injectables | BLA — approved | — | Dec 9 1991 | 2,201 | 186 |
| CellREDM | — | Injectables | No US authorization found | — | — | 158 | 106 |
| Daxxify | REVANCE THERAPEUTICS, INC. | Injectables | BLA — approved | — | Sep 7 2022 | 2,201 | 186 |
| Dysport | IPSEN BIOPHARM LTD | Injectables | BLA — approved | — | Apr 29 2009 | 2,201 | 186 |
| Ellansé | — | Injectables | No US authorization found | — | — | — | — |
| Elravie Re2O | — | Injectables | No US authorization found | — | — | 158 | 106 |
| Hylenex recombinant | HALOZYME THERAP | Injectables | BLA — approved | — | Dec 2 2005 | — | — |
| Jeuveau | EVOLUS INC | Injectables | BLA — approved | — | Feb 1 2019 | 2,201 | 186 |
| Juveacell | — | Injectables | No US authorization found | — | — | 158 | 106 |
| Juvederm Ultra XC | Allergan | Injectables | PMA — approved | — | Jan 7 2010 | 1,298 | 46 |
| Juvederm Volbella XC | Allergan | Injectables | PMA — approved | — | May 31 2016 | 1,298 | 46 |
| Juvederm Vollure XC | Allergan | Injectables | PMA — approved | — | Mar 17 2017 | 1,298 | 46 |
| Juvederm Voluma XC | Allergan | Injectables | PMA — approved | — | Oct 22 2013 | 1,298 | 46 |
| Juvederm Volux XC | Allergan | Injectables | PMA — approved | — | Jul 29 2022 | 1,298 | 46 |
| Kybella | ABBVIE | Injectables | NDA — approved | — | Apr 29 2015 | — | — |
| Letybo | HUGEL INC | Injectables | BLA — approved | — | Feb 29 2024 | 2,201 | 186 |
| Profhilo | — | Injectables | No US authorization found | — | — | 1,298 | 46 |
| Radiesse | Merz North America, Inc. | Injectables | PMA — approved | — | Dec 22 2006 | 582 | 7 |
| Rejuran | — | Injectables | No US authorization found | — | — | 155 | 16 |
| Restylane Defyne EU | Q-Med AB | Injectables | PMA — approved | — | Dec 9 2016 | 1,298 | 46 |
| Restylane Kysse EU | Q-Med AB | Injectables | PMA — approved | — | Mar 26 2020 | 1,298 | 46 |
| Restylane Lyft EU | Q-Med AB | Injectables | PMA — approved | — | Aug 31 2015 | 1,298 | 46 |
| Restylane Silk | Q-Med AB | Injectables | PMA — approved | — | Jun 13 2014 | 1,298 | 46 |
| Revanesse Versa | Prollenium Medical Technologies, Inc. | Injectables | PMA — approved | — | Oct 2 2017 | 1,298 | 46 |
| RHA Collection | Teoxane S.A. | Injectables | PMA — approved | — | Oct 19 2017 | 1,298 | 46 |
| Sculptra EU | Q-Med AB | Injectables | PMA — approved | — | Aug 3 2004 | 586 | 17 |
| SKINVIVE by Juvederm | Allergan | Injectables | PMA — approved | — | May 11 2023 | 1,298 | 46 |
| Xeomin | MERZ PHARMS | Injectables | BLA — approved | — | Jul 30 2010 | 2,201 | 186 |
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Curated seed list; study and trial counts are per modality, not per brand. What this measuresThis is a curated seed list of widely used medical-aesthetic products, each crosswalked to a real FDA record where one could be found with confidence. Being listed is not an endorsement, not a ranking and not a claim of market share. Being absent is not a judgement — it means the product is not in this seed list yet. Counts beside each filter are live counts of the products currently matching your other filters. Manufacturer is the applicant or sponsor field of the FDA record, printed exactly as FDA publishes it, so one company can appear under more than one string.
Methodology →
Sorted by most recent FDA decision — a filing date, not a quality signal. What each ordering measuresEvery ordering on this page is a proxy built from public records, never a quality judgement. Orders products by the most recent FDA decision date matched to the brand name, including later submissions and supplements. A recent date means the manufacturer filed again; it does not mean the product is newer, improved, more popular or better. Orders products by the number of PubMed records matching a fixed query for the product's MODALITY, never its brand name. It counts how much has been published about a technique. It is not a quality score, not an efficacy measure, not a count of randomised trials, and not comparable between techniques of different ages. Orders products by the number of ClinicalTrials.gov studies matching a fixed intervention-plus-condition query for the product's MODALITY, never its brand. Registration is not completion, not publication and not a result. Alphabetical by product name. No ranking, quality judgement or ordering of merit is implied by the position of anything in this list. Orders products by the earliest FDA decision date matched to the brand name. For drugs approved under a BLA or NDA the original approval can long predate any cosmetic indication, so an early date is not a cosmetic-use date.
Methodology →
Comparisons in this category
Botox Cosmetic vs botulinum toxin
Daxxify vs botulinum toxin
Dysport vs botulinum toxin
Jeuveau vs botulinum toxin
Profhilo vs hyaluronic acid filler
Xeomin vs botulinum toxin
Botox Cosmetic vs Daxxify
Botox Cosmetic vs Dysport
Botox Cosmetic vs Jeuveau
Botox Cosmetic vs Xeomin
Morpheus8 vs Sculptra
Which pairs exist is editorial — observed search demand, not a judgement about any product. What this measuresWhich brands get a comparison page is the ONE editorial decision on this site, and this is it stated plainly. Every brand with a comparison page was observed in a live Google or Bing autocomplete list on 2026-07-26 — that is the entire membership rule, and the seed query each brand was seen under is published in the source of this page. It is a record of what people type, not a judgement about the products: a brand with a page is not better, more popular or more recommended than a brand without one, and a brand without one is missing only because nobody has yet seen it in an autocomplete list. Nothing else on this site is chosen this way; every figure on the page below is copied mechanically from a public record.
Methodology →